神經(jīng)生長(cháng)因子β重組兔單克隆抗體

產(chǎn)品貨號：

BN42128R
中文名稱(chēng)：

神經(jīng)生長(cháng)因子β重組兔單克隆抗體
英文名稱(chēng)：

Rabbit anti-NGF Monoclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規格

售價(jià)

備注
BN42128R-50ul

50ul

￥2020.00

交叉反應：Mouse,Rat(predicted:Human,Zebrafish) 推薦應用：WB
BN42128R-100ul

100ul

￥3240.00

交叉反應：Mouse,Rat(predicted:Human,Zebrafish) 推薦應用：WB

產(chǎn)品描述

英文名稱(chēng)	NGF
中文名稱(chēng)	神經(jīng)生長(cháng)因子β重組兔單克隆抗體
別名	Beta nerve growth factor; NGF-beta; Beta nerve growth factor precursor; Beta NGF; HSAN5; MGC161426; MGC161428; Nerve growth factor beta; Nerve growth factor beta polypeptide; Nerve growth factor beta subunit; NGF B; NID67; NGF beta; NGF-B; NGF_HUMAN.
研究領(lǐng)域	發(fā)育生物學(xué) 神經(jīng)生物學(xué) 細胞因子
抗體來(lái)源	Rabbit
克隆類(lèi)型	Monoclonal
克隆號	11G1
交叉反應	Mouse, Rat, (predicted: Human, Zebrafish, )
產(chǎn)品應用	WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	13/32kDa
細胞定位	分泌型蛋白
性狀	Liquid
濃度	1mg/ml
免疫原	Recombinant human NGF:
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008] Function: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Subunit: Homodimer. Subcellular Location: Secreted. DISEASE: Defects in NGF are the cause of hereditary sensory and autonomic neuropathy type 5 (HSAN5) [MIM:608654]. The hereditary sensory and autonomic neuropathies are a genetically and clinically heterogeneous group of disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and by sensory and/or autonomic abnormalities. HSAN5 patients manifest loss of pain perception and impaired temperature sensitivity, ulcers, and in some cases self-mutilation. The autonomic involvement is variable. Similarity: Belongs to the NGF-beta family. SWISS: P01138 Gene ID: 4803 Database links: Entrez Gene: 4803 Human Entrez Gene: 18049 Mouse Entrez Gene: 310738 Rat Omim: 162030 Human SwissProt: P01138 Human SwissProt: P01139 Mouse SwissProt: P25427 Rat Unigene: 2561 Human Unigene: 1259 Mouse Unigene: 22168 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications