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    首頁(yè)>>免疫學(xué)>>一抗>>ADAM17重組兔單克隆抗體
    ADAM17重組兔單克隆抗體
    • 產(chǎn)品貨號:
      BN42068R
    • 中文名稱(chēng):
      ADAM17重組兔單克隆抗體
    • 英文名稱(chēng):
      Rabbit anti-ADAM17 (9E7) Monoclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產(chǎn)品規格

      售價(jià)

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    • BN42068R-50ul

      50ul

      ¥2020.00

      交叉反應:Human,Mouse(predicted:Rat) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN42068R-100ul

      100ul

      ¥3240.00

      交叉反應:Human,Mouse(predicted:Rat) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產(chǎn)品描述

    英文名稱(chēng)ADAM17 (9E7)
    中文名稱(chēng)ADAM17重組兔單克隆抗體
    別    名A disintegrin and metalloproteinase domain 17; ADAM 17; ADAM metallopeptidase domain 17; ADAM17 protein; CD 156b; CD156b; CD156b antigen; CSVP; MGC71942; Snake venom like protease; TACE; TNF alpha convertase; TNF alpha converting enzyme; Tumor Necrosis Factor Alpha Converting Enzyme; A disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADA17_HUMAN.  
    研究領(lǐng)域腫瘤  免疫學(xué)  神經(jīng)生物學(xué)  信號轉導  轉錄調節因子  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Monoclonal
    克 隆 號9E7
    交叉反應Human, Mouse,  (predicted: Rat, )
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:20-200 IHC-F=1:20-200 ICC=1:20-200 IF=1:20-200 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量93kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原Recombinant human ADAM17 protein:700-824/824 <Cytoplasmic>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq].

    Subunit:
    Interacts with MAD2L1, MAPK14 and MUC1.

    Subcellular Location:
    Membrane.

    Tissue Specificity:
    Ubiquitously expressed. Expressed at highest levels in adult heart, placenta, skeletal muscle, pancreas, spleen, thymus, prostate, testes, ovary and small intestine, and in fetal brain, lung, liver and kidney.

    Similarity:
    Contains 1 disintegrin domain.
    Contains 1 peptidase M12B domain.

    SWISS:
    P78536

    Gene ID:
    6868

    Database links:

    Entrez Gene: 6868 Human

    Entrez Gene: 11491 Mouse

    Entrez Gene: 57027 Rat

    Omim: 603639 Human

    SwissProt: P78536 Human

    SwissProt: Q9Z0F8 Mouse

    SwissProt: Q9Z1K9 Rat

    Unigene: 404914 Human

    Unigene: 27681 Mouse

    Unigene: 144585 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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