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    • 最近搜索：細胞培養 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>膜糖蛋白CD200抗體
    膜糖蛋白CD200抗體
    • 產(chǎn)品貨號：
      BN41932R
    • 中文名稱(chēng)：
      膜糖蛋白CD200抗體
    • 英文名稱(chēng)：
      Rabbit anti-CD200 Polyclonal antibody
    • 品牌：
      Biorigin

    • 貨號

      產(chǎn)品規格

      售價(jià)

      備注

    • BN41932R-50ul

      50ul

      ￥1486.00

      交叉反應：Human,Rat(predicted:Mouse) 推薦應用：IHC-P,IHC-F,IF,ELISA

    • BN41932R-100ul

      100ul

      ￥2360.00

      交叉反應：Human,Rat(predicted:Mouse) 推薦應用：IHC-P,IHC-F,IF,ELISA

    • BN41932R-200ul

      200ul

      ￥3490.00

      交叉反應：Human,Rat(predicted:Mouse) 推薦應用：IHC-P,IHC-F,IF,ELISA

    產(chǎn)品描述

    英文名稱(chēng)CD200
    中文名稱(chēng)膜糖蛋白CD200抗體
    別    名CD200; CD200 antigen; CD200 molecule; MOX1; MOX2; MRC; MRC OX 2 antigen; My033; OX 2; OX 2 membrane glycoprotein precursor; OX-2 membrane glycoprotein; OX2G; OX2G_HUMAN.  


    研究領(lǐng)域細胞生物  免疫學(xué)  細胞表面分子  糖蛋白  淋巴細胞  t-淋巴細胞  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應Human,  (predicted: Mouse, Rat, )
    產(chǎn)品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量28kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CD200:41-140/278 <Extracellular>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

    Function:
    Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.

    Subunit:
    Interacts with CD200R1.

    Subcellular Location:
    Cell membrane; Single-pass type I membrane protein.

    Similarity:
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    SWISS:
    P41217

    Gene ID:
    4345

    Database links:

    Entrez Gene: 4345 Human

    Omim: 155970 Human

    SwissProt: P41217 Human

    Unigene: 79015 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    CD200是Ⅰ型膜糖蛋白，為免疫球蛋白超家族的新成員，廣泛表達在人類(lèi)胸腺細胞、B細胞、激活的T細胞、濾泡狀樹(shù)突細胞、神經(jīng)元及血管內皮上?？杀磉_于B細胞及其增殖性疾病和一部分T細胞。近年來(lái)研究發(fā)現，CD200與CD200R間的相互作用可以傳遞抑制性信號減低髓樣細胞的活性，改變其遷移。CD200在免疫疾病和抑制排斥反應中作為一種免疫耐受信號，它的一些相關(guān)分子在免疫調節中也具有一定的作用。


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