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    • 最近搜索：細胞培養 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>雙調蛋白/結腸直腸細胞源性生長(cháng)因子抗體
    雙調蛋白/結腸直腸細胞源性生長(cháng)因子抗體
    • 產(chǎn)品貨號：
      BN41880R
    • 中文名稱(chēng)：
      雙調蛋白/結腸直腸細胞源性生長(cháng)因子抗體
    • 英文名稱(chēng)：
      Rabbit anti-Amphiregulin Polyclonal antibody
    • 品牌：
      Biorigin

    • 貨號

      產(chǎn)品規格

      售價(jià)

      備注

    • BN41880R-50ul

      50ul

      ￥1486.00

      交叉反應：Human,Mouse,Rat(predicted:Dog,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

    • BN41880R-100ul

      100ul

      ￥2360.00

      交叉反應：Human,Mouse,Rat(predicted:Dog,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

    • BN41880R-200ul

      200ul

      ￥3490.00

      交叉反應：Human,Mouse,Rat(predicted:Dog,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

    產(chǎn)品描述

    英文名稱(chēng)Amphiregulin
    中文名稱(chēng)雙調蛋白/結腸直腸細胞源性生長(cháng)因子抗體
    別    名AR; Colorectum cell derived growth factor; CRDGF; A REG; AR antibody; AREG; Colorectum cell derived growth factor; CRDGF; MGC13647; Schwannoma derived growth factor; SDGF; AREG_HUMAN.  


    研究領(lǐng)域腫瘤  細胞生物  免疫學(xué)  神經(jīng)生物學(xué)  生長(cháng)因子和激素  轉錄調節因子  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Dog, Cow, Horse, Rabbit, Sheep, )
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:ug/test IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量16kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Amphiregulin:185-252/252 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹Amphiregulin expression is induced by phorbol ester, estrogen, androgen, and other EGFR ligands. In vitro, amphiregulin functions as an autocrine growth stimulator to drive proliferation of colon carcinoma cells, normal and oncogene-transformed mammary epithelial cells, cervical carcinoma cells, prostate cancer cells, and keratinocytes. Amphiregulin is important in the development of human placenta and murine mammary gland. It is reportedly overexpressed in human cancers of breast, colon, stomach and pancreas.

    Function:
    Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.

    Subunit:
    The immature precursor interacts with CNIH.

    Subcellular Location:
    Membrane; Single-pass membrane protein.

    Similarity:
    Belongs to the amphiregulin family.
    Contains 1 EGF-like domain.

    SWISS:
    P15514

    Gene ID:
    374

    Database links:

    Entrez Gene: 374 Human

    Entrez Gene: 727738 Human

    Entrez Gene: 11839 Mouse

    Omim: 104640 Human

    SwissProt: P15514 Human

    SwissProt: P31955 Mouse

    Unigene: 270833 Human

    Unigene: 645475 Human

    Unigene: 8039 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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