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    • 最近搜索：細胞培養 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>肌原調節蛋白抗體
    肌原調節蛋白抗體
    • 產(chǎn)品貨號：
      BN41822R
    • 中文名稱(chēng)：
      肌原調節蛋白抗體
    • 英文名稱(chēng)：
      Rabbit anti-MyoD1/Myf3 Polyclonal antibody
    • 品牌：
      Biorigin

    • 貨號

      產(chǎn)品規格

      售價(jià)

      備注

    • BN41822R-50ul

      50ul

      ￥1486.00

      交叉反應：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep) 推薦應用：WB,ELISA

    • BN41822R-100ul

      100ul

      ￥2360.00

      交叉反應：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep) 推薦應用：WB,ELISA

    • BN41822R-200ul

      200ul

      ￥3490.00

      交叉反應：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep) 推薦應用：WB,ELISA

    產(chǎn)品描述

    英文名稱(chēng)MyoD1/Myf3
    中文名稱(chēng)肌原調節蛋白抗體
    別    名Myogenic differentiation 1; AI503393; bHLHc1; MD1; MGC156574; MYF3; MYOD; MYOD1; PUM; MYOD1_HUMAN; Class C basic helix-loop-helix protein 1; bHLHc1; Myogenic factor 3; Myf-3


    研究領(lǐng)域免疫學(xué)  發(fā)育生物學(xué)  轉錄調節因子  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量35kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from mouse MyoD1:51-150/318 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. [provided by RefSeq, Jul 2008]

    Function:
    Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins.

    Subunit:
    Efficient DNA binding requires dimerization with another bHLH protein. Seems to form active heterodimers with ITF-2. Interacts with SUV39H1 and CDK9. Interacts with DDX5.

    Subcellular Location:
    Nucleus.

    Post-translational modifications:
    Phosphorylated by CDK9. This phosphorylation promotes its function in muscle differentiation.
    Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely, its deacetylation by SIRT1 inhibits its function.
    Ubiquitinated on the N-terminus; which is required for proteasomal degradation

    Similarity:
    Contains 1 bHLH (basic helix-loop-helix) domain.

    SWISS:
    P10085

    Gene ID:
    17927

    Database links:

    Entrez Gene: 374048 Chicken

    Entrez Gene: 281938 Cow

    Entrez Gene: 4654 Human

    Entrez Gene: 17927 Mouse

    Entrez Gene: 407604 Pig

    Entrez Gene: 337868 Rat

    Entrez Gene: 443405 Sheep

    Omim: 159970 Human

    SwissProt: P16075 Chicken

    SwissProt: Q7YS82 Cow

    SwissProt: P15172 Human

    SwissProt: P10085 Mouse

    SwissProt: P49811 Pig

    SwissProt: Q02346 Rat

    SwissProt: P29331 Sheep

    Unigene: 181768 Human

    Unigene: 1526 Mouse

    Unigene: 9493 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
















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