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    • 最近搜索：細胞培養 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>細胞毒性受體NK-p46抗體
    細胞毒性受體NK-p46抗體
    • 產(chǎn)品貨號：
      BN41608R
    • 中文名稱(chēng)：
      細胞毒性受體NK-p46抗體
    • 英文名稱(chēng)：
      Rabbit anti-NCR1 Polyclonal antibody
    • 品牌：
      Biorigin

    • 貨號

      產(chǎn)品規格

      售價(jià)

      備注

    • BN41608R-50ul

      50ul

      ￥1486.00

      交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Sheep) 推薦應用：WB,ELISA

    • BN41608R-100ul

      100ul

      ￥2360.00

      交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Sheep) 推薦應用：WB,ELISA

    • BN41608R-200ul

      200ul

      ￥3490.00

      交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Sheep) 推薦應用：WB,ELISA

    產(chǎn)品描述

    英文名稱(chēng)NCR1
    中文名稱(chēng)細胞毒性受體NK-p46抗體
    別    名Natural killer cell p46-related protein; Natural cytotoxicity triggering receptor 1; NK-p46; NKp46; NK cell-activating receptor; Lymphocyte antigen 94 homolog; CD335; CD 335; LY94; NCTR1_HUMAN.  


    研究領(lǐng)域細胞生物  免疫學(xué)  信號轉導  轉錄調節因子  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Sheep, )
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量31kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CD335:198-206/304 <Extracellular>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

    Function:
    Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

    Subunit:
    Interacts with CD247 and FCER1G

    Subcellular Location:
    Cell membrane.

    Tissue Specificity:
    Selectively expressed by both resting and activated NK cells.

    Post-translational modifications:
    N-glycosylated.
    O-glycosylated.

    Similarity:
    Belongs to the natural cytotoxicity receptor (NCR) family.
    Contains 2 Ig-like (immunoglobulin-like) domains.

    SWISS:
    O76036

    Gene ID:
    9437

    Database links:

    Entrez Gene: 9437 Human

    Entrez Gene: 17086 Mouse

    Entrez Gene: 117547 Rat

    Omim: 604530 Human

    SwissProt: O76036 Human

    SwissProt: Q8C567 Mouse

    SwissProt: Q9Z0H5 Rat

    Unigene: 97084 Human

    Unigene: 240231 Mouse

    Unigene: 30049 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














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