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    首頁(yè)>>免疫學(xué)>>一抗>>香葉烯基轉移酶1β抗體
    香葉烯基轉移酶1β抗體
    • 產(chǎn)品貨號：
      BN41382R
    • 中文名稱(chēng)：
      香葉烯基轉移酶1β抗體
    • 英文名稱(chēng)：
      Rabbit anti-PGGT1B Polyclonal antibody
    • 品牌：
      Biorigin

    • 貨號

      產(chǎn)品規格

      售價(jià)

      備注

    • BN41382R-100ul

      100ul

      ￥2360.00

      交叉反應：Mouse,Rat(predicted:Human,Horse) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

    • BN41382R-200ul

      200ul

      ￥3490.00

      交叉反應：Mouse,Rat(predicted:Human,Horse) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

    產(chǎn)品描述

    英文名稱(chēng)PGGT1B
    中文名稱(chēng)香葉烯基轉移酶1β抗體
    別    名PGGT1B; GGTase-I beta; GGTase-1 beta; BGGI; Geranylgeranyl transferase type I subunit beta; Geranylgeranyl transferase type-1 subunit beta; GGTase-I-beta; GGTI; PGGT1B; PGTB1_HUMAN; Type I protein geranyl-geranyltransferase subunit beta;   
    研究領(lǐng)域細胞生物  免疫學(xué)  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應Mouse, Rat,  (predicted: Human, Horse, )
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量42kDa
    細胞定位細胞核 細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human PGGT1 beta:301-377/377 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]

    Function:
    Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Acts on the Rac1, Rac2, Rap1A and Rap1B proteins. The beta subunit is responsible for peptide-binding.

    Subunit:
    Heterodimer of an alpha and a beta subunit.

    Similarity:
    Belongs to the protein prenyltransferase subunit beta family.
    Contains 4 PFTB repeats.

    SWISS:
    P53609

    Gene ID:
    5229

    Database links:

    Entrez Gene: 5229 Human

    Entrez Gene: 225467 Mouse

    Entrez Gene: 81746 Rat

    Omim: 602031 Human

    SwissProt: P53609 Human

    SwissProt: Q8BUY9 Mouse

    SwissProt: P53610 Rat

    Unigene: 254006 Human

    Unigene: 262096 Mouse

    Unigene: 393044 Mouse

    Unigene: 10031 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications











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