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    • 最近搜索：細胞培養 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>著(zhù)絲粒蛋白O抗體
    著(zhù)絲粒蛋白O抗體
    • 產(chǎn)品貨號：
      BN41377R
    • 中文名稱(chēng)：
      著(zhù)絲粒蛋白O抗體
    • 英文名稱(chēng)：
      Rabbit anti-CENPO Polyclonal antibody
    • 品牌：
      Biorigin

    • 貨號

      產(chǎn)品規格

      售價(jià)

      備注

    • BN41377R-100ul

      100ul

      ￥2360.00

      交叉反應：nan(predicted:Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

    • BN41377R-200ul

      200ul

      ￥3490.00

      交叉反應：nan(predicted:Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

    產(chǎn)品描述

    英文名稱(chēng)CENPO
    中文名稱(chēng)著(zhù)絲粒蛋白O抗體
    別    名CENPO binds to the kinetochore. Its depletion from cells interferes with spindle assembly. It is necessary for correct binding of spindle checkpoint proteins to kinetochores. It is required for checkpoint signaling;   
    研究領(lǐng)域細胞生物  細胞周期蛋白  細胞分化  表觀(guān)遺傳學(xué)  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量34kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CENPO:101-200/300 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹CENPO binds to the kinetochore. Its depletion from cells interferes with spindle assembly. It is necessary for correct binding of spindle checkpoint proteins to kinetochores. It is required for checkpoint signaling.

    Function:
    Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex.

    Subunit:
    Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and MLF1IP/CENPU.

    Subcellular Location:
    Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.

    SWISS:
    Q9BU64

    Gene ID:
    79172

    Database links:

    Entrez Gene: 79172 Human

    Entrez Gene: 52504 Mouse

    Omim: 611504 Human

    SwissProt: Q9BU64 Human

    SwissProt: Q8K015 Mouse

    Unigene: 731569 Human

    Unigene: 70546 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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