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    • 最近搜索：細胞培養 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>垂體瘤細胞凋亡抗體
    垂體瘤細胞凋亡抗體
    • 產(chǎn)品貨號：
      BN41257R
    • 中文名稱(chēng)：
      垂體瘤細胞凋亡抗體
    • 英文名稱(chēng)：
      Rabbit anti-RHBDD3 Polyclonal antibody
    • 品牌：
      Biorigin

    • 貨號

      產(chǎn)品規格

      售價(jià)

      備注

    • BN41257R-100ul

      100ul

      ￥2360.00

      交叉反應：Human,Mouse(predicted:Rat) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

    • BN41257R-200ul

      200ul

      ￥3490.00

      交叉反應：Human,Mouse(predicted:Rat) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

    產(chǎn)品描述

    英文名稱(chēng)RHBDD3
    中文名稱(chēng)垂體瘤細胞凋亡抗體
    別    名C22orf3; HS984G1A; Pituitary tumor apoptosis; PTAG; RHBD3_HUMAN; RHBDD3; Rhomboid domain containing 3; Rhomboid domain-containing protein 3.  
    研究領(lǐng)域細胞生物  神經(jīng)生物學(xué)  細胞凋亡  轉錄調節因子  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, )
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量40kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human RHBDD3:151-250/386 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹PTAG is a novel 386 amino acid multi-pass membrane protein that contains one UBA domain and augments drug-induced apoptosis. Cells lacking PTAG have a reduced apoptotic response, thereby causing a predisposition to cell malignancy and resistance to chemotherapeutic interventions, and PTAG plays a role in colorectal tumorigenesis as the majority of primary colorectal tumors lack the PTAG gene. Encoded by a gene located on human chromosome 22, PTAG is often co-expressed with EWS (ewing sarcoma breakpoint region 1), a gene located directly downstream of PTAG.

    Subcellular Location:
    Membrane; Multi-pass membrane protein (Potential).

    Similarity:
    Contains 1 UBA domain

    SWISS:
    Q9Y3P4

    Gene ID:
    25807

    Database links:

    Entrez Gene: 25807 Human

    Entrez Gene: 279766 Mouse

    Entrez Gene: 289753 Rat

    SwissProt: Q9Y3P4 Human

    SwissProt: Q8BP97 Mouse

    SwissProt: Q642B3 Rat

    Unigene: 106730 Human

    Unigene: 260866 Mouse

    Unigene: 9606 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    RHBDD3分子是一個(gè)全新的TLR信號途徑的負向調控蛋白分子,是一個(gè)能夠顯著(zhù)抑制自身免疫性疾病發(fā)生的效應分子,RHBDD3控制機體避免發(fā)生過(guò)度的免疫應答、防止自身免疫性疾病的發(fā)生具有重要意義。













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