• <li id="mmmm8"></li>
  • <noscript id="mmmm8"></noscript>
    • <tt id="mmmm8"></tt>
    • 最近搜索：細胞培養 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>卷曲螺旋結構域蛋白50抗體
    卷曲螺旋結構域蛋白50抗體
    • 產(chǎn)品貨號：
      BN41236R
    • 中文名稱(chēng)：
      卷曲螺旋結構域蛋白50抗體
    • 英文名稱(chēng)：
      Rabbit anti-CCDC50 Polyclonal antibody
    • 品牌：
      Biorigin

    • 貨號

      產(chǎn)品規格

      售價(jià)

      備注

    • BN41236R-100ul

      100ul

      ￥2360.00

      交叉反應：Human,Mouse(predicted:Rat) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

    • BN41236R-200ul

      200ul

      ￥3490.00

      交叉反應：Human,Mouse(predicted:Rat) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

    產(chǎn)品描述

    英文名稱(chēng)CCDC50
    中文名稱(chēng)卷曲螺旋結構域蛋白50抗體
    別    名C3orf6; C3orf6 YMER; CCD50_HUMAN; CCDC 50; Ccdc50; Chromosome 3 open reading frame 6; Coiled coil domain containing 50; Coiled coil domain containing protein 50; Coiled-coil domain-containing protein 50; Protein Ymer; Ymer; Ymer protein.   
    研究領(lǐng)域細胞生物  免疫學(xué)  表觀(guān)遺傳學(xué)  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, )
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量34kDa
    細胞定位細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CCDC50:251-306/306 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].

    Function:
    Involved in EGFR signaling.

    Tissue Specificity:
    Isoform 1 and isoform 2 are co-expressed in placenta, liver, lung, kidney and pancreas. Only isoform 1 is detected in skeletal muscle, brain and heart.

    Post-translational modifications:
    Phosphorylated on tyrosine residues.

    DISEASE:
    Defects in CCDC50 are the cause of deafness autosomal dominant type 44 (DFNA44) . A form of non-syndromic hearing loss. It is initially moderate and affects mainly low to mid frequencies. Later, it progresses to involve all the frequencies and leads to a profound hearing loss by the 6th decade. The onset of the hearing loss occurs in the first decade of life.

    SWISS:
    Q8IVM0

    Gene ID:
    152137

    Database links:

    Entrez Gene: 152137 Human

    Entrez Gene: 67501 Mouse

    Entrez Gene: 288022 Rat

    SwissProt: Q8IVM0 Human

    SwissProt: Q3TNK7 Mouse

    SwissProt: Q3TRW1 Mouse

    SwissProt: Q810U5 Mouse

    SwissProt: Q810U0 Rat

    Unigene: 478682 Human

    Unigene: 258985 Mouse

    Unigene: 9610 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


    99久久精品费精品国产一区二区,色黄性日韩在线,天天操夜夜操,成人试看120秒体验区