線(xiàn)粒體乙?；?抗體

產(chǎn)品貨號：

BN41131R
中文名稱(chēng)：

線(xiàn)粒體乙?；?抗體
英文名稱(chēng)：

Rabbit anti-SIRT3 Polyclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規格

售價(jià)

備注
BN41131R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse(predicted:Rat) 推薦應用：WB,IHC-P,IHC-F,ICC

產(chǎn)品描述

英文名稱(chēng)	SIRT3
中文名稱(chēng)	線(xiàn)粒體乙?；?抗體
別名	hSIRT3; hSIRT 3; hSIRT3; Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase; NAD dependent deacetylase sirtuin 3 mitochondrial; NAD-dependent deacetylase sirtuin-3, mitochondrial; Silent mating type information regulation 2 S.cerevisiae homolog 3; Sir 2 like 3; SIR 2 like protein 3; SIR 3; SIR2 L3; Sir2 like 3; SIR2 like protein 3; SIR2-like protein 3; SIR2L3; SIRT 3; SIRT3_HUMAN; Sirtuin 3; Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae); Sirtuin type 3; Sirtuin3.
研究領(lǐng)域	腫瘤心血管細胞生物細胞周期蛋白線(xiàn)粒體
抗體來(lái)源	Rabbit
克隆類(lèi)型	Polyclonal
交叉反應	Human, Mouse, (predicted: Rat, )
產(chǎn)品應用	WB=1:500-1000 IHC-P=1:20-50 IHC-F=1:20-50 ICC=1:100 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	28/43kDa
細胞定位	細胞漿線(xiàn)粒體
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human SIRT3:300-399/399
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
產(chǎn)品介紹	NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels. Function: NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels. Subunit: Interacts with NDUFA9, ACSS1, IDH2 and GDH. Subcellular Location: Mitochondrion matrix. Tissue Specificity: Widely expressed. Post-translational modifications: Processed by mitochondrial processing peptidase (MPP) to give a 28 kDa product. Such processing is probably essential for its enzymatic activity. Similarity: Belongs to the sirtuin family. Contains 1 deacetylase sirtuin-type domain. SWISS: Q9NTG7 Gene ID: 23410 Database links: Entrez Gene: 23410 Human Entrez Gene: 64384 Mouse Omim: 604481 Human SwissProt: Q9NTG7 Human SwissProt: Q8R104 Mouse Unigene: 716456 Human Unigene: 244216 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.