自噬相關(guān)蛋白4A抗體

產(chǎn)品貨號：

BN40975R
中文名稱(chēng)：

自噬相關(guān)蛋白4A抗體
英文名稱(chēng)：

Rabbit anti-ATG4A Polyclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規格

售價(jià)

備注
BN40975R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse,Rat(predicted:Cow,Rabbit) 推薦應用：IHC-P,IHC-F,IF,ELISA
BN40975R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse,Rat(predicted:Cow,Rabbit) 推薦應用：IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱(chēng)	ATG4A
中文名稱(chēng)	自噬相關(guān)蛋白4A抗體
別名	AI627006 ; APG4 autophagy 4 homolog A ; Apg4a ; ATG4 autophagy related 4 homolog A (S. cerevisiae) ; ATG4 autophagy related 4 homolog A ; ATG4A ; ATG4A_HUMAN ; Atg4al ; AUT like 2 cysteine endopeptidase ; AUT-like 2 cysteine endopeptidase ; Autl2 ; Autophagin 2 ; Autophagin-2 ; Autophagy related 4A cysteine peptidase ; Autophagy related cysteine endopeptidase 2 ; Autophagy related protein 4 homolog A ; Autophagy-related cysteine endopeptidase 2 ; Autophagy-related protein 4 homolog A ; AV169859 ; Cysteine protease ATG4A ; hAPG4A ; MGC107179 .
研究領(lǐng)域	腫瘤免疫學(xué) 細胞凋亡轉錄調節因子
抗體來(lái)源	Rabbit
克隆類(lèi)型	Polyclonal
交叉反應	Human, Mouse, Rat, (predicted: Cow, Rabbit, )
產(chǎn)品應用	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	45kDa
細胞定位	細胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human ATG4A:51-150/398
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	ATG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Function: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Subcellular Location: Cytoplasm (Probable). Tissue Specificity: Widely expressed, at a low level, and the highest expression is observed in skeletal muscle and brain. Also detected in fetal liver. Similarity: Belongs to the peptidase C54 family. SWISS: Q8WYN0 Gene ID: 115201 Database links: Entrez Gene: 115201 Human Entrez Gene: 666468 Mouse Omim: 300663 Human SwissProt: Q8WYN0 Human SwissProt: Q8C9S8 Mouse Unigene: 8763 Human Unigene: 102230 Mouse Unigene: 393320 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.