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    • 最近搜索：細胞培養 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>HOXB4抗體
    HOXB4抗體
    • 產(chǎn)品貨號：
      BN40942R
    • 中文名稱(chēng)：
      HOXB4抗體
    • 英文名稱(chēng)：
      Rabbit anti-HOXB4 Polyclonal antibody
    • 品牌：
      Biorigin

    • 貨號

      產(chǎn)品規格

      售價(jià)

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    • BN40942R-100ul

      100ul

      ￥2360.00

      交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    • BN40942R-200ul

      200ul

      ￥3490.00

      交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    產(chǎn)品描述

    英文名稱(chēng)HOXB4
    中文名稱(chēng)HOXB4抗體
    別    名Homeo box 2F; Homeo box B4; Homeobox 2F; Homeobox B4; Homeobox protein Hox B4; Homeobox protein HoxB4; HOX 2; Hox 2.6; Hox 2F; HOX B4; HOX2; HOX-2 Hox2.6; Hox2F; HOXB 4; HOXB-4.  
    研究領(lǐng)域腫瘤  免疫學(xué)  信號轉導  干細胞  轉錄調節因子  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Sheep, )
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量28kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human HOXB4:151-251/251 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹HOXB4 is a homeodomain-containing transcription factor with diverse roles in embryonic development and the regulation of adult stem cells. It promotes proliferation of hematopoietic stem cells and can both activate and repress apoptosis.

    Function:
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

    Subcellular Location:
    Nucleus.

    Similarity:
    Belongs to the Antp homeobox family. Deformed subfamily.
    Contains 1 homeobox DNA-binding domain.

    SWISS:
    P17483

    Gene ID:
    3214

    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    OXB4通過(guò)激活不同的信號通路增強HSC的自我更新,同時(shí)又不影響維持正常穩態(tài)造血的調控機制。提高HOXB4的表達水平,能夠極大地增強HSC的自我更新功能,但基本不影響細胞的分化、系特異性及終末細胞的形態(tài)和功能。另外，HOXB4還可增強胚胎干細胞(embryonic stem cell,ESC)的造血潛能,促進(jìn)ESC向造血細胞分化。


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