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  • 最近搜索:細胞培養 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>磷酸化蛋白激酶GCN2蛋白抗體
    磷酸化蛋白激酶GCN2蛋白抗體
    • 產(chǎn)品貨號:
      BN40868R
    • 中文名稱(chēng):
      磷酸化蛋白激酶GCN2蛋白抗體
    • 英文名稱(chēng):
      Rabbit anti-phospho-GCN2 (Thr667) Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產(chǎn)品規格

      售價(jià)

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    • BN40868R-100ul

      100ul

      ¥2470.00

      交叉反應:Mouse,Rat(predicted:Human,Dog,Cow,Horse) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產(chǎn)品描述

    英文名稱(chēng)phospho-GCN2 (Thr667)
    中文名稱(chēng)磷酸化蛋白激酶GCN2蛋白抗體
    別    名GCN2 (phospho T667); p-GCN2 (phospho T667); EIF2AK4; Eukaryotic Translation Initiation Factor 2-alpha kinase 4; GCN2-like protein; KIAA1338; E2AK4_HUMAN; Eif2ak4; Eukaryotic Translation Initiation Factor 2 alpha kinase 4; GCN2; GCN2 eIF2alpha kinase; GCN2-like protein; MGCN2.  
    產(chǎn)品類(lèi)型磷酸化抗體 
    研究領(lǐng)域細胞生物  神經(jīng)生物學(xué)  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應Mouse, Rat,  (predicted: Human, Dog, Cow, Horse, )
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量181kDa
    細胞定位細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated Synthesised phosphopeptide derived from human GCN2 around the phosphorylation site of Thr667:PG(p-T)PP 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹GCN2 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2 to downregulate protein synthesis in response to varied cellular stresses.

    Tissue Specificity:
    Widely expressed.

    Post-translational modifications:
    Autophosphorylated on threonine residues.

    Similarity:
    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.
    Contains 2 protein kinase domains.
    Contains 1 RWD domain.

    SWISS:
    Q9P2K8

    Gene ID:
    440275

    Database links:

    Entrez Gene: 440275 Human

    Entrez Gene: 27103 Mouse

    Entrez Gene: 114859 Rat

    Omim: 609280 Human

    SwissProt: Q9P2K8 Human

    SwissProt: Q9QZ05 Mouse

    Unigene: 656673 Human

    Unigene: 217616 Mouse

    Unigene: 8333 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    GCN2蛋白的作用;可能是將短期記憶變成長(cháng)期記憶的一個(gè)主控調節因子, GCN2蛋白在長(cháng)期記憶形成中功能的發(fā)現將可能幫助研究人員開(kāi)發(fā)出提高記憶力喪失的病人提高記憶力。


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