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    首頁(yè)>>免疫學(xué)>>一抗>>CD8抗體
    CD8抗體
    • 產(chǎn)品貨號：
      BN40722R
    • 中文名稱(chēng)：
      CD8抗體
    • 英文名稱(chēng)：
      Rabbit anti-CD8 Polyclonal antibody
    • 品牌：
      Biorigin

    • 貨號

      產(chǎn)品規格

      售價(jià)

      備注

    • BN40722R-100ul

      100ul

      ￥2360.00

      交叉反應：Human 推薦應用：WB

    • BN40722R-200ul

      200ul

      ￥3490.00

      交叉反應：Human 推薦應用：WB

    產(chǎn)品描述

    英文名稱(chēng)CD8
    中文名稱(chēng)CD8抗體
    別    名CD8 antigen, alpha polypeptide (p32); CD8a; CD8a antigen; CD8a molecule; CD8A_HUMAN; Leu2; Leu2 T lymphocyte antigen; MAL; OKT8 T cell antigen; p32; T cell antigen Leu2; T cell co receptor; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; T8 T cell antigen.  
    研究領(lǐng)域細胞生物  免疫學(xué)  干細胞  細胞表面分子  細胞類(lèi)型標志物  淋巴細胞  t-淋巴細胞  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應Human, 
    產(chǎn)品應用WB=1:500-2000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量27kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CD8:1-100/235  <Extracellular>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

    Function:
    Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.

    Subunit:
    In general heterodimer of an alpha and a beta chain linked by two disulfide bonds. Can also form homodimers.

    Subcellular Location:
    Membrane; Single-pass type I membrane protein.

    Similarity:
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    SWISS:
    P01732

    Gene ID:
    925

    Database links:

    Entrez Gene: 925 Human

    Entrez Gene: 926 Human

    Entrez Gene: 12525 Mouse

    Entrez Gene: 12526 Mouse

    Omim: 186910 Human

    SwissProt: P01732 Human

    SwissProt: P10966 Human

    SwissProt: P01731 Mouse

    SwissProt: P10300 Mouse

    Unigene: 405667 Human

    Unigene: 85258 Human

    Unigene: 1858 Mouse

    Unigene: 333148 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications


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