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    • 最近搜索：細胞培養 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>單羧酸轉運蛋白2抗體
    單羧酸轉運蛋白2抗體
    • 產(chǎn)品貨號：
      BN40682R
    • 中文名稱(chēng)：
      單羧酸轉運蛋白2抗體
    • 英文名稱(chēng)：
      Rabbit anti-MCT2 Polyclonal antibody
    • 品牌：
      Biorigin

    • 貨號

      產(chǎn)品規格

      售價(jià)

      備注

    • BN40682R-100ul

      100ul

      ￥2360.00

      交叉反應：Mouse,Rat 推薦應用：WB,ELISA

    • BN40682R-200ul

      200ul

      ￥3490.00

      交叉反應：Mouse,Rat 推薦應用：WB,ELISA

    產(chǎn)品描述

    英文名稱(chēng)MCT2
    中文名稱(chēng)單羧酸轉運蛋白2抗體
    別    名MCT 2; MCT; Monocarboxylate transporter 2; MonocarboxylateTransporter 2; MOT2; MOT2_HUMAN; SLC16A7; Solute carrier family 16 member 7; Solute carrier Family 16 Monocarboxylic Acid Transporters Member 7.  
    研究領(lǐng)域腫瘤  細胞生物  免疫學(xué)  信號轉導  轉運蛋白  新陳代謝  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應Mouse, Rat, 
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量52kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from mouse MCT2 :411-478/478 <Cytoplasmic>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters (MCTs) mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate (summary by Lin et al., 1998 [PubMed 9786900]).[supplied by OMIM, Feb 2011].

    Function:
    Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter.

    Subunit:
    Interacts with GRID2IP.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein.

    Tissue Specificity:
    High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells.

    Similarity:
    Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

    SWISS:
    O70451

    Gene ID:
    20503

    Database links:

    Entrez Gene: 9194 Human

    Omim: 603654 Human

    SwissProt: O60669 Human

    Unigene: 439643 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications















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