細胞纖毛內轉運同源蛋白46抗體

產(chǎn)品貨號：

BN40465R
中文名稱(chēng)：

細胞纖毛內轉運同源蛋白46抗體
英文名稱(chēng)：

Rabbit anti-IFT46 Polyclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規格

售價(jià)

備注
BN40465R-100ul

100ul

￥2360.00

交叉反應：Human 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
BN40465R-200ul

200ul

￥3490.00

交叉反應：Human 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱(chēng)	IFT46
中文名稱(chēng)	細胞纖毛內轉運同源蛋白46抗體
別名	C11orf2; C11orf60; IFT46; IFT46_HUMAN; Intraflagellar transport protein 46 homolog.
研究領(lǐng)域	細胞生物信號轉導細胞骨架
抗體來(lái)源	Rabbit
克隆類(lèi)型	Polyclonal
交叉反應	Human,
產(chǎn)品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	34kDa
細胞定位	細胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human IFT46:101-200/304
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	IFT46 is a 304 amino acid protein that belongs to the IFT46 family. IFT46 localizes to the cilium basal body but can also be found along the length of the cilium and is a part of a complex involved in intraflagellar transport (IFT). In addition, IFT46 is involved in the bi-directional movement of particles that is required for the assembly, maintenance, and functionality of primary cilia. Furthermore, IFT46 may be involved in skeletogenesis and chondrocyte maturation. Two isoforms exist due to alternate splicing events and the gene encoding IFT46 maps to human chromosome 11. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. Function: Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity). Subunit: Part of the IFT complex B. Interacts with IFT57, IFT88 and DAW1 (By similarity). Subcellular Location: Cytoplasm, cytoskeleton, cilium basal body (By similarity). Cell projection, cilium (By similarity). Note=Expression is concentrated at the cilium basal body but is also detected along the length of the cilium (By similarity). Similarity: Belongs to the IFT46 family. SWISS: Q9NQC8 Gene ID: 56912 Database links: Entrez Gene: 56912 Human SwissProt: Q9NQC8 Human Unigene: 533738 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications