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    • 最近搜索：細胞培養 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>冷休克蛋白DBPA抗體
    冷休克蛋白DBPA抗體
    • 產(chǎn)品貨號：
      BN40401R
    • 中文名稱(chēng)：
      冷休克蛋白DBPA抗體
    • 英文名稱(chēng)：
      Rabbit anti-DBPA Polyclonal antibody
    • 品牌：
      Biorigin

    • 貨號

      產(chǎn)品規格

      售價(jià)

      備注

    • BN40401R-100ul

      100ul

      ￥2360.00

      交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

    • BN40401R-200ul

      200ul

      ￥3490.00

      交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

    產(chǎn)品描述

    英文名稱(chēng)DBPA
    中文名稱(chēng)冷休克蛋白DBPA抗體
    別    名Cold shock domain containing protein A; Cold shock domain-containing protein A; csdA; CSDA1; DBPA; DNA binding protein A; DNA-binding protein A; Single strand DNA binding protein NF GMB; Single-strand DNA-binding protein NF-GMB; ZO 1 associated nucleic acid binding protein; ZO1 associated nucleic acid binding protein; ZONAB; YBOX3_HUMAN; Y-box-binding protein 3.  
    研究領(lǐng)域細胞生物  信號轉導  細胞周期蛋白  轉錄調節因子  表觀(guān)遺傳學(xué)  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Rabbit, Sheep, )
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量40kDa
    細胞定位細胞核 細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human DBPA/CSDA1:165-270/372 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹CSDA is a 372 amino acid nuclear and cytoplasmic protein that is highly expressed in skeletal muscle and heart. Containing one CSD (cold-shock) domain, CSDA is thought to bind to GM-CSF promoter, full length mRNA and to short RNA sequences containing a specific consensus site. CSDA is suggested to have a role in translation repression and is found in a mRNP complex with MSY2. MSY2 belongs to the Y-box family of multifunctional proteins that regulate both transcription and translation. CSDA participates in promoting cell proliferation and expression of cyclin D1 and proliferating cell nuclear antigen (PCNA). CSDA is regarded to be an important component of the mechanisms that sense epithelial density and in regulating the switch between proliferation and differentiation through complex transcriptional networks.

    Function:
    Binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression.

    Subcellular Location:
    Cytoplasm. Nucleus.

    Tissue Specificity:
    Highly expressed in skeletal muscle and heart.

    Similarity:
    Contains 1 CSD (cold-shock) domain.

    SWISS:
    P16989

    Gene ID:
    8531

    Database links:

    Entrez Gene: 8531 Human

    Entrez Gene: 56449 Mouse

    Entrez Gene: 83807 Rat

    Omim: 603437 Human

    SwissProt: P16989 Human

    SwissProt: Q61478 Mouse

    SwissProt: Q68G78 Mouse

    SwissProt: Q8BPG0 Mouse

    SwissProt: Q9JKB3 Mouse

    SwissProt: Q3KRC7 Rat

    SwissProt: Q62764 Rat

    Unigene: 221889 Human

    Unigene: 299604 Mouse

    Unigene: 458000 Mouse

    Unigene: 3306 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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