神經(jīng)降壓素受體2抗體

產(chǎn)品貨號：

BN40344R
中文名稱(chēng)：

神經(jīng)降壓素受體2抗體
英文名稱(chēng)：

Rabbit anti-Neurotensin Receptor 2 Polyclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規格

售價(jià)

備注
BN40344R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse(predicted:Rat,Dog,Cow,Rabbit,Sheep) 推薦應用：WB,ELISA
BN40344R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse(predicted:Rat,Dog,Cow,Rabbit,Sheep) 推薦應用：WB,ELISA

產(chǎn)品描述

英文名稱(chēng)	Neurotensin Receptor 2
中文名稱(chēng)	神經(jīng)降壓素受體2抗體
別名	Levocabastine sensitive neurotensin receptor; Levocabastine-sensitive neurotensin receptor; Neurotensin receptor type 2; NT R 2; NT-R-2; NTR2; NTR2 receptor; NTR2_HUMAN; Ntsr2.
研究領(lǐng)域	細胞生物神經(jīng)生物學(xué) 信號轉導細胞膜受體 G蛋白偶聯(lián)受體 G蛋白信號
抗體來(lái)源	Rabbit
克隆類(lèi)型	Polyclonal
交叉反應	Mouse, (predicted: Human, Rat, Dog, Cow, Rabbit, Sheep, )
產(chǎn)品應用	WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	45kDa
細胞定位	細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human Neurotensin Receptor 2:151-250/410 <Extracellular>
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNF?in an ERK1/2 and Akt kinase-dependent manner. Function: Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. Neurotensin receptor subfamily. NTSR2 sub-subfamily. SWISS: O95665 Gene ID: 23620 Database links: Entrez Gene: 23620 Human Entrez Gene: 18217 Mouse Entrez Gene: 64636 Rat Omim: 605538 Human SwissProt: O95665 Human SwissProt: P70310 Mouse SwissProt: Q63384 Rat Unigene: 131138 Human Unigene: 281715 Mouse Unigene: 127792 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.