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    • 最近搜索：細胞培養 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>鋅指蛋白318抗體
    鋅指蛋白318抗體
    • 產(chǎn)品貨號：
      BN40303R
    • 中文名稱(chēng)：
      鋅指蛋白318抗體
    • 英文名稱(chēng)：
      Rabbit anti-ZNF318 Polyclonal antibody
    • 品牌：
      Biorigin

    • 貨號

      產(chǎn)品規格

      售價(jià)

      備注

    • BN40303R-100ul

      100ul

      ￥2360.00

      交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Horse,Rabbit) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

    • BN40303R-200ul

      200ul

      ￥3490.00

      交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Horse,Rabbit) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

    產(chǎn)品描述

    英文名稱(chēng)ZNF318
    中文名稱(chēng)鋅指蛋白318抗體
    別    名Endocrine Regulatory Protein; HGNC13578; HRIHFB2436; ZFP318; Zinc Finger Protein 318; ZN318_HUMAN.  
    研究領(lǐng)域細胞生物  神經(jīng)生物學(xué)  信號轉導  內分泌病  鋅指蛋白  表觀(guān)遺傳學(xué)  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Dog, Pig, Horse, Rabbit, )
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量251kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human ZNF318:1077-1125/2279 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹ZNF318 is a 2279 amino acid endocrine regulatory protein that localizes to the nucleus. Highly expressed in testis, ovaries and kidneys, ZNF318 is a co-repressor of androgen receptor (AR)-mediated transcriptional activation and is thought to regulate transcription during spermatogenesis. ZNF318 interacts with the N-terminal domain of AR and contains two matrin-type zinc fingers. Two isoforms of ZNF318, designated TZF and TZF-L, are produced due to alternative splicing events. Each of these splice variants are thought to have unique roles in transcriptional regulation. While the TZF isoform functions as a repressor of AR-mediated transcriptional activation, the TZF-L isoform is thought to enhance AR-mediated transcriptional activation.

    Function:
    ZNF318 encodes a nuclear protein with a zinc finger motif of the Cys2-His2 type that is a novel corepressor of androgen receptor.

    Subunit:
    Interacts with the N-terminal domain of AR.

    Subcellular Location:
    Nuclear.

    Tissue Specificity:
    Expressed in endocrine tissue.

    Post-translational modifications:
    Phosphorylated upon DNA damage, probably by ATM or ATR.

    Similarity:
    Contains 2 matrin-type zinc fingers.

    SWISS:
    Q5VUA4

    Gene ID:
    24149

    Database links:

    Entrez Gene: 24149 Human

    SwissProt: Q5VUA4 Human

    SwissProt: Q99PP2 Mouse

    Unigene: 509718 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














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